Paul L. Modrich is an American biochemist known for his groundbreaking research in the field of molecular biology. He was awarded the Nobel Prize in Chemistry in 2015 for his work on DNA repair mechanisms, which are crucial for maintaining the integrity of genetic information in cells. His studies have significantly advanced our understanding of how cells fix errors in their DNA, which has implications for cancer research and treatment. Modrich earned his Ph.D. from Duke University and has held various academic positions, including at Duke and the Howard Hughes Medical Institute. His contributions to science have made him a prominent figure in the study of genetics and cellular processes.