The Palazzo della Cancelleria is a historic building located in Rome, Italy. Constructed in the late 15th century, it serves as the headquarters of the Vatican's Apostolic Chancellery. The architecture showcases a blend of Renaissance and Mannerist styles, featuring a grand façade and an impressive courtyard. Inside, the palace houses important artworks and frescoes, including works by notable artists such as Raphael. The building is significant not only for its architectural beauty but also for its role in the administration of the Catholic Church. It remains a key site for understanding the history of the Vatican.