PI3K/Akt
The PI3K/Akt pathway is a crucial signaling mechanism in cells that helps regulate various functions, including growth, survival, and metabolism. PI3K (phosphoinositide 3-kinase) is activated by various signals, leading to the activation of Akt, a protein that promotes cell survival and growth by inhibiting apoptosis (programmed cell death).
This pathway is important in many biological processes and is often implicated in diseases, particularly cancer. Abnormal activation of the PI3K/Akt pathway can lead to uncontrolled cell proliferation and resistance to therapies, making it a significant target for cancer treatment research.