Non-depolarizing agents are a class of muscle relaxants used primarily during surgical procedures to facilitate intubation and improve surgical conditions. They work by blocking the action of the neurotransmitter acetylcholine at the neuromuscular junction, preventing muscle contraction without causing initial muscle twitching. These agents are often preferred in anesthesia because they allow for better control of muscle relaxation. Common examples include vecuronium and rocuronium. Unlike depolarizing agents, they do not cause muscle fasciculations, making them suitable for patients with certain medical conditions or those at risk for complications.