Nitrogen mustard refers to a group of chemical compounds derived from mustard gas, which was originally used as a chemical warfare agent. These compounds contain nitrogen in their structure and are known for their ability to interfere with DNA replication. Due to this property, nitrogen mustards have been developed as chemotherapy agents for treating certain types of cancer, such as lymphoma and leukemia. The most common nitrogen mustards include mechlorethamine, cyclophosphamide, and ifosfamide. These drugs work by damaging the DNA of rapidly dividing cancer cells, ultimately leading to cell death. While effective in cancer treatment, nitrogen mustards can also cause side effects, including nausea, hair loss, and increased risk of infection.