Mitragyna is a genus of tropical trees in the family Rubiaceae, primarily found in Southeast Asia. The most well-known species is Mitragyna speciosa, commonly known as kratom. This plant has been used traditionally for its stimulant and sedative effects, depending on the dosage. The leaves of kratom contain compounds that interact with opioid receptors in the brain, leading to various effects such as pain relief and mood enhancement. However, the use of kratom has raised concerns regarding safety and potential for addiction, prompting discussions about regulation in several countries.