Missouri State Route 50 is a major east-west highway in the state of Missouri. It spans approximately 200 miles, connecting the cities of Kansas City and Washington. The route serves as an important thoroughfare for both local and regional traffic, facilitating access to various communities along its path. The highway passes through several counties, including Bates, Henry, and Cole. It intersects with other significant routes, such as Interstate 70 and U.S. Route 63, enhancing connectivity within the state's transportation network. Missouri State Route 50 is vital for commerce and travel in the region.