Missouri State Route 19 is a north-south highway located in the central part of Missouri. It spans approximately 150 miles, connecting the towns of Cuba and Hannibal. The route serves as a vital link for local communities and provides access to various recreational areas. The highway runs through scenic landscapes, including parts of the Ozark National Scenic Riverways. It intersects with several major roads, enhancing connectivity for travelers and residents alike. Missouri State Route 19 is maintained by the Missouri Department of Transportation and plays an essential role in the state's transportation network.