Mary Wotton, Lady Grey (c. 1490–1558), was an English noblewoman known for her marriage to Thomas Grey, 2nd Marquess of Dorset. She was the daughter of Sir Edward Wotton and Mary Browne, and her family was part of the English gentry. Lady Grey played a role in the political landscape of her time, particularly during the reign of King Henry VIII. As a member of the Grey family, she was connected to significant historical events, including the English Reformation. Lady Grey's life was marked by the challenges faced by noble families during periods of political upheaval, including the shifting allegiances of the Tudor court.