Manganese SOD, or manganese superoxide dismutase, is an important enzyme found in the mitochondria of cells. It plays a crucial role in protecting cells from oxidative stress by converting harmful superoxide radicals into less harmful molecules, such as hydrogen peroxide and oxygen. This process helps maintain cellular health and function. Manganese SOD is particularly significant in organisms that experience high levels of oxidative stress, such as those exposed to environmental toxins or intense physical activity. It requires manganese, an essential trace mineral, as a cofactor for its activity, highlighting the importance of proper nutrition for optimal enzyme function.