The Malaria Vaccine Initiative (MVI) is a global effort aimed at developing and distributing effective vaccines to combat malaria, a life-threatening disease caused by parasites transmitted through the bites of infected mosquitoes. MVI is part of the broader PATH organization, which focuses on improving health and saving lives through innovative solutions. One of the key achievements of MVI is the development of the RTS,S/AS01 vaccine, which has shown promise in reducing malaria cases in young children. The initiative collaborates with various partners, including governments and research institutions, to ensure that vaccines are accessible and affordable in regions most affected by malaria, particularly in sub-Saharan Africa.