The Machupo virus is a type of virus that causes a severe illness known as Bolivian hemorrhagic fever. It is primarily found in Bolivia and is transmitted to humans through contact with infected rodents, particularly the Calomys callosus species. Symptoms can include fever, fatigue, and bleeding, which can lead to serious complications. First identified in the 1960s, the Machupo virus is part of the Arenaviridae family. It is considered a biosafety level 4 pathogen due to its potential to cause outbreaks. Preventive measures focus on controlling rodent populations and avoiding contact with infected animals.