MAOIs, or Monoamine Oxidase Inhibitors, are a class of antidepressant medications used to treat depression and anxiety disorders. They work by blocking the action of the enzyme monoamine oxidase, which breaks down neurotransmitters like serotonin, norepinephrine, and dopamine in the brain. By preventing this breakdown, MAOIs help increase the levels of these mood-regulating chemicals, potentially improving symptoms of depression. While effective, MAOIs require dietary restrictions to avoid serious interactions with certain foods and medications. Foods high in tyramine, such as aged cheeses and cured meats, can cause dangerous spikes in blood pressure when consumed with MAOIs. Therefore, patients on these medications must be closely monitored and educated about safe dietary choices.