Monoamine Oxidase Inhibitors (MAOIs) are a class of medications used primarily to treat depression and anxiety disorders. They work by blocking the action of the enzyme monoamine oxidase, which breaks down neurotransmitters like serotonin, norepinephrine, and dopamine in the brain. By inhibiting this enzyme, MAOIs help increase the levels of these important chemicals, potentially improving mood and emotional well-being. While effective, MAOIs require dietary restrictions to avoid serious interactions with certain foods and medications. Foods high in tyramine, such as aged cheeses and cured meats, can cause dangerous spikes in blood pressure when consumed with MAOIs. Therefore, patients must be closely monitored and educated about these risks when prescribed this type of medication.