MAO-B, or monoamine oxidase B, is an enzyme found primarily in the brain. It plays a crucial role in breaking down neurotransmitters, such as dopamine, which are important for mood regulation and motor control. By metabolizing these chemicals, MAO-B helps maintain a balance in the brain's signaling pathways. Inhibiting MAO-B can be beneficial in treating certain conditions, such as Parkinson's disease and depression. Medications that block this enzyme can increase the levels of dopamine, potentially improving symptoms and enhancing overall brain function. Understanding MAO-B is essential for developing effective therapies for these disorders.