Lyme Disease symptoms can vary widely but often begin with a characteristic rash called erythema migrans, which appears as a red circle with a lighter center. Other early symptoms may include fever, chills, fatigue, and muscle or joint aches. If left untreated, Lyme Disease can lead to more severe symptoms, such as joint pain, neurological issues, and heart problems. These later symptoms may develop weeks to months after the initial infection, highlighting the importance of early detection and treatment.