Louise Jefferson is a fictional character from the television show The Jeffersons, which aired from 1975 to 1985. She is portrayed by actress Isabel Sanford and is the wife of George Jefferson, a successful businessman. Louise is known for her strong personality, intelligence, and supportive nature, often balancing her husband's more outspoken demeanor. In the series, Louise is depicted as a loving mother to their son, Lionel Jefferson, and is involved in various social issues. The show addresses themes of race, class, and family dynamics, with Louise often serving as a voice of reason amidst the comedic situations.