Wheezy Jefferson is a fictional character from the television show The Jeffersons, which aired from 1975 to 1985. She is portrayed by actress Isabel Sanford and is known for her distinctive voice and humorous personality. Wheezy is the wife of George Jefferson, the show's main character, and together they navigate life in their upscale apartment in Manhattan. Wheezy is characterized by her strong-willed nature and her ability to stand up to her husband, often providing a balance to George's more brash demeanor. The character became iconic for her role in representing African American women on television during a time when such portrayals were limited.