Lipodystrophy is a medical condition characterized by abnormal distribution of body fat. Individuals with lipodystrophy may experience loss of fat in certain areas, such as the arms and legs, while accumulating fat in others, like the abdomen or face. This condition can be associated with metabolic issues, including insulin resistance and increased risk of diabetes. There are various types of lipodystrophy, which can be genetic or acquired. Genetic forms, such as Berardinelli-Seip congenital lipodystrophy, are present at birth, while acquired forms can result from factors like HIV treatment or malnutrition. Management often involves addressing metabolic complications and improving body image.