Leigh Syndrome is a rare genetic disorder that primarily affects the central nervous system. It is characterized by progressive neurological decline, often beginning in infancy or early childhood. Symptoms may include developmental delays, loss of motor skills, seizures, and respiratory problems. The condition is caused by mutations in genes responsible for energy production in cells. Diagnosis typically involves clinical evaluation, imaging studies like MRI, and genetic testing. There is currently no cure for Leigh Syndrome, and treatment focuses on managing symptoms and improving quality of life. Life expectancy varies, but many affected individuals may have a shortened lifespan.