Leflore County is located in the state of Mississippi, in the United States. It was established in 1870 and is named after James Leflore, a prominent local figure. The county seat is Greenwood, which serves as the largest city in the area. Leflore County is known for its rich agricultural history, particularly in cotton production. The county covers an area of approximately 1,200 square miles and is part of the Mississippi Delta region. It features a mix of rural landscapes and small towns, with a population that reflects the diverse culture of the region. Key highways, such as U.S. Route 49, provide access to surrounding areas.