A "Large Integer" refers to an integer that exceeds the typical size limits of standard data types in programming languages. While most programming languages can handle integers up to a certain size, large integers can represent much bigger values, often used in fields like cryptography, scientific computing, and data analysis. To manage large integers, specialized libraries or data types, such as BigInt in JavaScript or BigInteger in Java, are utilized. These tools allow for arithmetic operations on numbers that can have hundreds or thousands of digits, enabling precise calculations that standard integer types cannot accommodate.