Nuclear Lamina
The nuclear lamina is a dense fibrillar network found inside the nucleus of eukaryotic cells. It is primarily composed of proteins called lamins, which provide structural support and help maintain the shape of the nucleus. This network plays a crucial role in organizing chromatin and anchoring nuclear pores, which are essential for the transport of molecules in and out of the nucleus.
In addition to its structural functions, the nuclear lamina is involved in various cellular processes, including DNA replication and cell division. It also helps regulate gene expression by influencing the spatial organization of the genome within the nucleus. Disruptions in the nuclear lamina can lead to various diseases, including certain types of muscular dystrophy and premature aging syndromes.