Keyhouse is a fictional house featured in the comic book series Locke & Key, created by Joe Hill and Gabriel Rodríguez. It serves as the central setting for the story, where the Locke family discovers magical keys that unlock various powers and abilities. Each key has unique properties, allowing characters to explore different dimensions and realities. The house itself is filled with secrets and hidden rooms, reflecting the family's history and the challenges they face. As the story unfolds, Keyhouse becomes a symbol of both safety and danger, representing the struggle between good and evil in the lives of the Locke family.