Karma Chakme was a prominent Tibetan Buddhist master and scholar, known for his teachings and writings in the 17th century. He is particularly recognized for his contributions to the Nyingma school of Tibetan Buddhism, where he emphasized the importance of meditation and the practice of compassion. Chakme is best known for his work, the Three Words that Strike the Vital Point, which outlines essential teachings on the nature of mind and the path to enlightenment. His teachings continue to influence practitioners and scholars within the Tibetan Buddhist tradition today.