KRT2, or Keratin 2, is a type of protein that belongs to the keratin family. It is primarily found in the skin, hair, and nails, playing a crucial role in providing structural support and protection. Keratins are essential for maintaining the integrity of epithelial cells, which form the outer layer of the skin. This protein is particularly important in the formation of the epidermis, the outermost layer of the skin. Mutations in the KRT2 gene can lead to various skin disorders, highlighting its significance in dermatological health. Understanding KRT2 helps researchers develop treatments for conditions related to skin and hair.