Japanese Encephalitis Virus (JEV) is a mosquito-borne virus that primarily affects the central nervous system. It is mainly transmitted through the bite of infected Culex mosquitoes, particularly in rural areas of Asia and Pacific Islands. The virus can cause inflammation of the brain, leading to severe neurological symptoms and, in some cases, death. Most people infected with JEV do not show symptoms, but those who do may experience fever, headache, and confusion. Vaccination is available and recommended for individuals living in or traveling to high-risk areas. Preventive measures include using mosquito repellent and wearing protective clothing.