The Isabella Stewart Gardner Museum is located in Boston, Massachusetts and was founded by Isabella Stewart Gardner in 1903. The museum is known for its unique architecture, resembling a Venetian palace, and houses an extensive collection of art, including works by Rembrandt, Vermeer, and Titian. The museum's layout is designed to resemble a 15th-century Italian villa, featuring a beautiful courtyard filled with plants and flowers. It is also famous for the unsolved art heist in 1990, where 13 pieces of art, valued at around $500 million, were stolen and remain missing.