Intrinsic Pathway
The intrinsic pathway is a crucial part of the blood coagulation process, which helps the body stop bleeding. This pathway is activated when blood comes into contact with damaged blood vessels, leading to a series of reactions involving various proteins known as clotting factors. These factors work together to form a stable blood clot.
In the intrinsic pathway, the activation of Factor XII triggers a cascade of events that ultimately activates Factor X. This leads to the conversion of prothrombin into thrombin, which then converts fibrinogen into fibrin, forming the mesh that stabilizes the clot. This pathway is essential for effective hemostasis.