The House of Hohenstaufen was a prominent dynasty in medieval Europe, ruling the Holy Roman Empire from the 12th to the 13th centuries. Founded by Frederick I, also known as Frederick Barbarossa, the family played a significant role in European politics, promoting the power of the emperor and engaging in conflicts with the papacy. The Hohenstaufen lineage included notable rulers such as Frederick II, who was known for his cultural contributions and conflicts with the Pope. The dynasty's influence waned after the death of Conrad IV in 1254, leading to a fragmented empire and the rise of regional powers.