The House of Guelders was a noble family in the Low Countries, primarily associated with the region of Guelders in present-day Netherlands. It played a significant role in the political landscape of medieval Europe, often engaging in conflicts with neighboring territories and dynasties. Founded in the 11th century, the house produced several notable rulers, including Duke Reginald IV and Duke Charles of Guelders. The family's influence peaked during the 15th century, but it eventually declined due to territorial losses and dynastic struggles, leading to its absorption into the House of Habsburg.