The House of Cleves was a noble family in the region of Cleves, located in present-day Germany. It played a significant role in the politics of the Holy Roman Empire during the late Middle Ages and the Renaissance. The family is best known for its connection to the English monarchy through Anne of Cleves, the fourth wife of King Henry VIII. The House of Cleves was part of the larger Duchy of Cleves, which was influential in the 15th and 16th centuries. The family often engaged in strategic marriages and alliances, enhancing their power and influence in European affairs. Their legacy includes contributions to art and culture in the region.