The House of Lusignan was a noble family that originated in the region of Lusignan in western France. It rose to prominence in the medieval period, particularly during the 12th and 13th centuries. The family is known for its connections to various European royal houses and its rule over territories such as Cyprus and parts of Syria during the Crusades. Members of the House of Lusignan played significant roles in the politics and conflicts of the time, including the Kingdom of Jerusalem. Their lineage included several kings and queens, and they were influential in shaping the history of the regions they governed. The family's legacy is marked by both their achievements and their eventual decline.