The Hofmann Rearrangement is a chemical reaction that transforms primary amides into primary amines with one fewer carbon atom. This process involves the treatment of the amide with a halogen, typically bromine or chlorine, in the presence of a strong base like sodium hydroxide. The reaction proceeds through the formation of an isocyanate intermediate, which is then hydrolyzed to yield the amine. This rearrangement is significant in organic chemistry for synthesizing amines, which are important in pharmaceuticals and other chemical industries. The Hofmann Rearrangement is named after the German chemist August Wilhelm von Hofmann, who discovered the reaction in the 19th century.