Hirschsprung's disease is a congenital condition that affects the large intestine, causing problems with bowel movements. It occurs when certain nerve cells, called ganglion cells, do not develop in a segment of the intestine, leading to a lack of muscle contractions needed for moving stool. This results in a blockage, causing constipation and abdominal swelling. Diagnosis typically involves a physical examination, imaging tests, and sometimes a biopsy of the intestine. Treatment usually requires surgery to remove the affected portion of the bowel, allowing for normal bowel function. Early diagnosis and intervention are crucial for better outcomes.