Hirschsprung's Disease is a congenital condition that affects the large intestine, causing problems with bowel movements. It occurs when nerve cells, called ganglion cells, do not develop in a segment of the intestine, leading to a lack of muscle contractions needed for moving stool. This results in a blockage, which can cause severe constipation and abdominal swelling. Diagnosis typically occurs in newborns or young children, often through physical exams and imaging tests. Treatment usually involves surgery to remove the affected portion of the intestine, allowing for normal bowel function. Early intervention is crucial for preventing complications.