High-level programming refers to coding languages that are designed to be easy for humans to read and write. These languages, such as Python, Java, and Ruby, abstract away the complex details of the computer's hardware, allowing programmers to focus on solving problems and developing applications. High-level languages use syntax and commands that resemble natural language, making them more accessible to beginners. In contrast to low-level programming languages, which are closer to machine code, high-level languages provide features like automatic memory management and built-in functions. This makes it easier to create software without needing to understand the intricate workings of the computer. High-level programming is essential for developing modern applications, websites, and software systems.