Henry de Vere, 16th Earl of Oxford (1593–1625), was an English nobleman known for his involvement in the court of King James I. He was the son of Edward de Vere, 15th Earl of Oxford and inherited the title after his father's death. His life was marked by a series of legal disputes and financial difficulties, which were common among the nobility of the time. The 16th Earl was also known for his connections to the arts and literature, particularly during the Elizabethan era. He was a patron of various writers and artists, contributing to the cultural landscape of England. Despite his challenges, his legacy remains tied to the rich history of the English aristocracy.