Hematoxylin and Eosin (H&E) is a widely used staining technique in histology, the study of tissues. Hematoxylin stains cell nuclei blue, highlighting their structure, while eosin stains the cytoplasm and extracellular matrix pink. This contrast allows for clear visualization of tissue architecture under a microscope. H&E staining is essential for diagnosing diseases, particularly in pathology. It helps pathologists identify abnormal cells and tissue changes, aiding in the detection of conditions such as cancer. The simplicity and effectiveness of H&E make it a standard method in laboratories worldwide.