HMG-CoA Reductase Inhibitors, commonly known as statins, are a class of medications used to lower cholesterol levels in the blood. They work by blocking the enzyme HMG-CoA reductase, which plays a crucial role in the production of cholesterol in the liver. By reducing cholesterol levels, statins help decrease the risk of heart disease and stroke. These medications are often prescribed to individuals with high cholesterol or those at risk for cardiovascular issues. Common examples of statins include atorvastatin, simvastatin, and rosuvastatin. While generally well-tolerated, they can have side effects, such as muscle pain or liver enzyme changes.