HERC2 is a gene located on chromosome 15 that plays a crucial role in the body's cellular processes. It is part of the HERC family of genes, which are involved in tagging proteins for degradation, helping to regulate various cellular functions. Variations in the HERC2 gene have been linked to different health conditions, including certain types of cancer and Alzheimer's disease. One of the most studied aspects of HERC2 is its association with eye color. Research has shown that specific variations in this gene can influence the production of melanin, the pigment responsible for eye color. This has made HERC2 a significant focus in genetic studies related to pigmentation traits.