H&E staining, or Hematoxylin and Eosin staining, is a widely used technique in histology to visualize tissue samples under a microscope. Hematoxylin stains cell nuclei blue, highlighting the genetic material, while Eosin stains the cytoplasm and extracellular matrix pink. This contrast allows for the differentiation of various tissue components. The process involves fixing the tissue sample, embedding it in paraffin, and then slicing it into thin sections. After applying the stains, the sections are examined to identify cellular structures and diagnose diseases, making H&E staining essential in pathology and medical research.