The Fundamental Theorem of Calculus connects the concepts of differentiation and integration, two core operations in calculus. It states that if a function is continuous on a closed interval, then the integral of that function can be computed using its antiderivative. This means that finding the area under a curve can be achieved by evaluating the antiderivative at the endpoints of the interval. Additionally, the theorem shows that the derivative of the integral of a function is the original function itself. This relationship highlights how integration and differentiation are inverse processes, providing a powerful tool for solving problems in mathematics and applied fields.