Fumarate is a chemical compound that plays a crucial role in the body's metabolism. It is an intermediate in the Krebs cycle, which is essential for energy production in cells. Fumarate is formed from succinate and is converted into malate during this cycle, helping to generate ATP, the energy currency of the cell. In addition to its metabolic functions, fumarate is also used in medical treatments. For instance, fumaric acid esters are used to treat certain skin conditions like psoriasis and are also being studied for their potential benefits in treating multiple sclerosis.