The Frisco Railroad, officially known as the St. Louis-San Francisco Railway, was a major American railroad that operated primarily in the central United States. Founded in 1876, it connected cities like St. Louis and Tulsa, facilitating trade and travel across several states. The railroad played a significant role in the economic development of the regions it served. In 1980, the Frisco Railroad merged with the Burlington Northern Railroad, becoming part of a larger network. The legacy of the Frisco continues today, as its routes and infrastructure have influenced modern rail transportation in the United States.