Fourth Avenue is a major street in various cities across the United States, often serving as a central thoroughfare. In cities like New York and Seattle, it is known for its vibrant atmosphere, featuring shops, restaurants, and cultural landmarks. The avenue typically connects different neighborhoods, making it a vital part of urban transportation. In New York City, Fourth Avenue runs through several boroughs and has historical significance, once being a key route for horse-drawn carriages. In Seattle, it is known for its proximity to the University of Washington and various entertainment venues, contributing to the city's lively character.