Ferrets are prone to several diseases that can affect their health. Common conditions include insulinoma, a tumor of the pancreas that leads to low blood sugar, and adrenal gland disease, which causes hormonal imbalances. Symptoms may include weight loss, lethargy, and changes in appetite or behavior. Another significant concern is ferret distemper, a highly contagious viral disease that can be fatal. Vaccination is crucial to prevent this illness. Additionally, heart disease and lymphoma are also seen in ferrets, particularly as they age. Regular veterinary check-ups can help detect these issues early and improve outcomes.