FLI1 is a gene that encodes a protein belonging to the ETS family of transcription factors. It plays a crucial role in regulating gene expression during various biological processes, including cell growth and differentiation. FLI1 is particularly important in the development of the hematopoietic system and is involved in the formation of blood cells. Mutations or alterations in the FLI1 gene can lead to various health issues, including certain types of cancer, such as Ewing sarcoma. This cancer primarily affects children and young adults and is characterized by the presence of a specific chromosomal translocation involving FLI1. Understanding FLI1's function is essential for developing targeted therapies for related diseases.