FLCN
FLCN, or FLCN gene, is a gene located on chromosome 17 that plays a crucial role in regulating cell growth and division. It encodes a protein known as folliculin, which is involved in various cellular processes, including energy metabolism and the response to nutrient availability. Mutations in the FLCN gene can lead to health issues, particularly Birt-Hogg-Dubé syndrome, a genetic condition characterized by skin tumors, lung cysts, and an increased risk of kidney cancer.
The FLCN protein interacts with several other proteins and pathways, influencing cellular signaling and tumor suppression. Understanding the function of FLCN is essential for developing potential therapies for conditions associated with its mutations. Ongoing research continues to explore its role in cancer biology and metabolic regulation.