Expedition 25 was a mission to the International Space Station (ISS) that took place from October 2010 to March 2011. This expedition involved a crew of six astronauts who conducted scientific research and maintenance tasks aboard the ISS. The crew included members from NASA, Roscosmos, and ESA. During Expedition 25, the crew performed various experiments in fields such as biology, physics, and Earth sciences. They also prepared for the arrival of the HTV-2 cargo spacecraft and supported the ongoing assembly of the ISS. The mission contributed to the understanding of long-duration spaceflight effects on the human body.